Freeze-fracture of reconstituted model membranes used as targets for cell-mediated cytotoxicity
Identifieur interne : 000C39 ( Main/Exploration ); précédent : 000C38; suivant : 000C40Freeze-fracture of reconstituted model membranes used as targets for cell-mediated cytotoxicity
Auteurs : S. Qasim Mehdi [États-Unis] ; J. Todd Lewis [États-Unis] ; Bruce R. Copeland [États-Unis] ; Harden M. Mcconnell [États-Unis]Source :
- BBA - Biomembranes [ 0005-2736 ] ; 1980.
English descriptors
- KwdEn :
Abstract
In a recent communication (Hollander, N., Mehdi, S.Q., Weissman, I.L., McConnell, H.M. and Kriss, J.P. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4042–4045) we reported that reconstituted model membranes containing murine tumor cell membrane proteins can be substituted for living cells as targets for cell-mediated cytolysis by allosensitized T-lymphocytes. The specificity of the lytic process was governed by the appropriate histocompatibility antigen (H-2). It was stressed, however, that although a standard protocol was faithfully followed for the reconstitution of the target membrane vesicle, the system was not uniformly reproducible. Some experiments showed high levels of specific vesicle killing while no lysis was observed in others. This work extends our description of the structural requirements of reconstituted membrane vesicles.
Url:
DOI: 10.1016/0005-2736(80)90461-7
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000247
- to stream Istex, to step Curation: 000240
- to stream Istex, to step Checkpoint: 000B90
- to stream Main, to step Merge: 000C46
- to stream Main, to step Curation: 000C39
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Freeze-fracture of reconstituted model membranes used as targets for cell-mediated cytotoxicity</title><author><name sortKey="Qasim Mehdi, S" sort="Qasim Mehdi, S" uniqKey="Qasim Mehdi S" first="S." last="Qasim Mehdi">S. Qasim Mehdi</name></author><author><name sortKey="Todd Lewis, J" sort="Todd Lewis, J" uniqKey="Todd Lewis J" first="J." last="Todd Lewis">J. Todd Lewis</name></author><author><name sortKey="Copeland, Bruce R" sort="Copeland, Bruce R" uniqKey="Copeland B" first="Bruce R." last="Copeland">Bruce R. Copeland</name></author><author><name sortKey="Mcconnell, Harden M" sort="Mcconnell, Harden M" uniqKey="Mcconnell H" first="Harden M." last="Mcconnell">Harden M. Mcconnell</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CDF0C0D54819689FAEB1D5A791C5A9DF3301727D</idno><date when="1980" year="1980">1980</date><idno type="doi">10.1016/0005-2736(80)90461-7</idno><idno type="url">https://api.istex.fr/document/CDF0C0D54819689FAEB1D5A791C5A9DF3301727D/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000247</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000247</idno><idno type="wicri:Area/Istex/Curation">000240</idno><idno type="wicri:Area/Istex/Checkpoint">000B90</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000B90</idno><idno type="wicri:doubleKey">0005-2736:1980:Qasim Mehdi S:freeze:fracture:of</idno><idno type="wicri:Area/Main/Merge">000C46</idno><idno type="wicri:Area/Main/Curation">000C39</idno><idno type="wicri:Area/Main/Exploration">000C39</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Freeze-fracture of reconstituted model membranes used as targets for cell-mediated cytotoxicity</title><author><name sortKey="Qasim Mehdi, S" sort="Qasim Mehdi, S" uniqKey="Qasim Mehdi S" first="S." last="Qasim Mehdi">S. Qasim Mehdi</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Division of Nuclear Medicine, Stanford University, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Todd Lewis, J" sort="Todd Lewis, J" uniqKey="Todd Lewis J" first="J." last="Todd Lewis">J. Todd Lewis</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Stauffer Laboratory for Physical Chemistry, Stanford University, Stanford</wicri:cityArea></affiliation><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>∗Present address: Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20205</wicri:regionArea><wicri:noRegion>MD 20205</wicri:noRegion></affiliation></author><author><name sortKey="Copeland, Bruce R" sort="Copeland, Bruce R" uniqKey="Copeland B" first="Bruce R." last="Copeland">Bruce R. Copeland</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Stauffer Laboratory for Physical Chemistry, Stanford University, Stanford</wicri:cityArea></affiliation><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>∗∗Present address: Division of Medical Genetics, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mcconnell, Harden M" sort="Mcconnell, Harden M" uniqKey="Mcconnell H" first="Harden M." last="Mcconnell">Harden M. Mcconnell</name><affiliation></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Stauffer Laboratory for Physical Chemistry, Stanford University, Stanford</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">BBA - Biomembranes</title><title level="j" type="abbrev">BBAMEM</title><idno type="ISSN">0005-2736</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1980">1980</date><biblScope unit="volume">600</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="590">590</biblScope><biblScope unit="page" to="594">594</biblScope></imprint><idno type="ISSN">0005-2736</idno></series><idno type="istex">CDF0C0D54819689FAEB1D5A791C5A9DF3301727D</idno><idno type="DOI">10.1016/0005-2736(80)90461-7</idno><idno type="PII">0005-2736(80)90461-7</idno><idno type="ArticleID">80904617</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0005-2736</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>(T-cell)</term><term>Cytotoxicity</term><term>Freeze-fracture electron microscopy</term><term>Model membrane</term><term>Reconstitution</term><term>Transplantation antigen</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In a recent communication (Hollander, N., Mehdi, S.Q., Weissman, I.L., McConnell, H.M. and Kriss, J.P. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4042–4045) we reported that reconstituted model membranes containing murine tumor cell membrane proteins can be substituted for living cells as targets for cell-mediated cytolysis by allosensitized T-lymphocytes. The specificity of the lytic process was governed by the appropriate histocompatibility antigen (H-2). It was stressed, however, that although a standard protocol was faithfully followed for the reconstitution of the target membrane vesicle, the system was not uniformly reproducible. Some experiments showed high levels of specific vesicle killing while no lysis was observed in others. This work extends our description of the structural requirements of reconstituted membrane vesicles.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Washington (État)</li></region><settlement><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Qasim Mehdi, S" sort="Qasim Mehdi, S" uniqKey="Qasim Mehdi S" first="S." last="Qasim Mehdi">S. Qasim Mehdi</name></region><name sortKey="Copeland, Bruce R" sort="Copeland, Bruce R" uniqKey="Copeland B" first="Bruce R." last="Copeland">Bruce R. Copeland</name><name sortKey="Copeland, Bruce R" sort="Copeland, Bruce R" uniqKey="Copeland B" first="Bruce R." last="Copeland">Bruce R. Copeland</name><name sortKey="Mcconnell, Harden M" sort="Mcconnell, Harden M" uniqKey="Mcconnell H" first="Harden M." last="Mcconnell">Harden M. Mcconnell</name><name sortKey="Todd Lewis, J" sort="Todd Lewis, J" uniqKey="Todd Lewis J" first="J." last="Todd Lewis">J. Todd Lewis</name><name sortKey="Todd Lewis, J" sort="Todd Lewis, J" uniqKey="Todd Lewis J" first="J." last="Todd Lewis">J. Todd Lewis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/MagnificatV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C39 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C39 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= MagnificatV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:CDF0C0D54819689FAEB1D5A791C5A9DF3301727D
|texte= Freeze-fracture of reconstituted model membranes used as targets for cell-mediated cytotoxicity
}}
| This area was generated with Dilib version V0.6.31. |  |